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Biotin-Beta-Amyloid 1-42 | Biotin-Aβ 1-42
來源:
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作者:jienitai
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發布時間: 2019-10-15
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567 次瀏覽
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分享到:
Biotin-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Biotin - Beta-Amyloid 1-42 | Biotin - Aβ 1-42
| 貨號 | 數量 | 價格（元） | 貨期 | ||
| BA-42-T-1 | 1 mg | ￥900.00 | 1~2天 | ||
| BA-42-T-5 | 5 mg | 詢價 | 1~2天 | ||
| BA-42-T-10 | 10 mg | 詢價 | 1~2天 | ||
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| 純度： | >95% | ||||
| 序列： | Biotin-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA | ||||
| Biotin-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala | |||||
| CAS No.: | / | ||||
| 分子式： | 102577-21-9 | ||||
| 分子量： | 4740.4 | ||||
| 等電點： | 4.7 | ||||
| 凈電荷(PH=7)： | -3.7 | ||||
| 平均親水性： | -0.1 | ||||
| 親水殘基比例： | 31% | ||||
| 外觀： | 白色粉末 | ||||
| 鹽： | TFA | ||||
| 來源： | 化學合成 | ||||
| 儲存條件(凍干粉)： | -20°C（1年） 或 -80°C（1-2年） | ||||
| 溶解條件： | Acetic acid/water (3:2) or DMSO | ||||
| 運輸條件： | 常溫（加冰袋） | ||||
| 描述： | Biotin (N-terminus) labeled Beta-amyloid 1-42 (Aβ 1-42). Beta amyloid 1?42 (Aβ1-42) is a self-associating peptide whose neurotoxic derivatives are thought to play a role in Alzheimer’s pathogenesis. | ||||
| 參考： |
1, Diffusible, nonfibrillar ligands derived from Aβ1–42
are potent central nervous system neurotoxins M. P. Lambert, A. K. Barlow, B. A. Chromy, C. Edwards and W. L. Klein; PNAS May 26, 1998 95 (11) 6448-6453 2, Self-Assembly of Aβ1-42 into Globular Neurotoxins Brett A. Chromy, Richard J. Nowak, Mary P. Lambert and William L. Klein; Biochemistry 2003, 42, 44, 12749–12760 3, High-Level Neuronal Expression of Aβ1–42 in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu, Margaret Mallory, Edward M. Rockenstein, Kelly Johnson-Wood and Lisa McConlogue; Journal of Neuroscience 1 June 2000, 20 (11) 4050-4058 |
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