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Beta-Amyloid 1-42 | Aβ 1-42, mouse, rat
來源:
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作者:jienitai
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發布時間: 2020-10-03
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550 次瀏覽
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DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Beta-Amyloid 1-42 | Aβ 1-42, mouse, rat
| 貨號 | 數量 | 價格（元） | 貨期 | ||
| A-42-M-1 | 1 mg | ￥1500.00 | 1~2天 | ||
| A-42-M-5 | 5 mg | 詢價 | 1~2天 | ||
| A-42-M-10 | 10 mg | 詢價 | 1~2天 | ||
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| 英文別名： | Aβ42 | Aβ1-42 | Abeta42 | Abeta 1-42 | Amyloid-β42 | β-Amyloid 1-42, mouse, rat | ||||
| 中文名： | 鼠：β-淀粉樣多肽 1-42 | Beta-淀粉樣多肽 1-42 | Beta-淀粉樣多肽 -42 | Β-淀粉樣多肽(1-42) | Beta-Amyloid多肽(1-42) | ||||
| 純度： | >95% by HPLC | ||||
| 序列(單字母)： | DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA | ||||
| (三字母序列)： | H - Asp - Ala - Glu - Phe - Gly - His - Asp - Ser - Gly - Phe - Glu - Val - Arg - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH | ||||
| CAS No.： | / | ||||
| 分子量： | 4418.01 | ||||
| 外觀： | 白色粉末 | ||||
| 等電點： | 4.7 | ||||
| 凈電荷(PH=7)： | -2.8 | ||||
| 平均親水性： | -0.1 | ||||
| 親水殘基比例： | 31% | ||||
| 鹽： | TFA | ||||
| 來源： | 化學合成 | ||||
| 儲存條件(凍干粉)： | -20°C（1年） 或 -80°C（1-2年） | ||||
| 溶解條件： | Acetic acid/water (3:2) or DMSO | ||||
| 運輸條件： | 常溫（加冰袋） | ||||
| 描述： | Insoluble deposits of β-amyloid (Aβ) are associated to neurodegenerative pathologies, in particular Alzheimer’s Disease (AD). The toxicity of synthetic amyloid-like peptides has been largely demonstrated and shown to depend upon their aggregation state. | ||||
| 參考： |
1, Anxiolytic and antidepressant profile of the
methanolic extract of Piper nigrum fruits in beta-amyloid (1–42) rat
model of Alzheimer’s disease Lucian Hritcu, Jaurès A Noumedem, Oana Cioanca, Monica Hancianu, Paula Postu & Marius Mihasan; Behavioral and Brain Functions; volume 11, Article number: 13 (2015) 2, Methanolic Extract of Piper nigrum Fruits Improves Memory Impairment by Decreasing Brain Oxidative Stress in Amyloid Beta(1–42) Rat Model of Alzheimer’s Disease Lucian Hritcu, Jaurès A. Noumedem, Oana Cioanca, Monica Hancianu, Victor Kuete & Marius Mihasan; Cellular and Molecular Neurobiology; volume 34, pages437–449(2014) 3，Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats S.Arancibia, M.Silhol, F.Moulière, J.Meffre, I.H?llinger, T.Maurice, L.Tapia-Arancibia; Neurobiology of Disease; Volume 31, Issue 3, September 2008, Pages 316-326 |
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